What is Molecular diagnostics?

Molecular diagnostics often provides objective, quantitative measurements that inform every stage of medical care - from risk assessment, screening, diagnosis, prognosis, therapy selection to monitoring of medical conditions.

“Molecular diagnostics” is a very broad term describing a class of diagnostic tests that assess a person’s health by applying clinical diagnosis at a molecular and genetic level. It is relied on testing and measuring specific genetic sequences in deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) or the proteins that being expressed. The kinds of specimens for testing covering blood, excreta, tissue fluid swabs, biopsies and others.

The expansion in the use of molecular diagnostic tests will continue and likely to be accelerated at a fast pace with the everyday new discoveries and developments. We are now entering into a new era in molecular diagnostics (DNA test and RNA test) and aligning well with the new trend of personalized healthcare.

DNA RNA Protein DNA RNA Protein

Facility

Acecgt Diagnostic has an on-site, state-of-the-art DNA testing laboratory, which is equipped with the latest automated and analytical instruments to ensure the highest accuracy from sample processing to analysis. We are staffed with qualified technologists and scientists who have substantial laboratory operations experience in the field.

AD performs the test following a specific standard operation protocol. We are firmly committed to the highest quality of service to our customers.  As part of the services, we adhere to strict standards of privacy.

Technology

Acecgt Diagnostic offers a full range of molecular diagnostics test services (DNA tests and RNA tests) and is adopting sophisticated and cutting edge technologies to enable medical professions in making critical decisions for their patients.

Quantitative Polymerase chain reaction (Q-PCR)

Quantitative polymerase chain reaction is the technique of molecular biology based on the polymerase chain reaction (PCR), which amplify and simultaneously detect or quantify the targeted DNA molecule of interest.

Quantitative Reverse Transcription real-time polymerase chain reaction (Q-RT PCR)

Quantitative Reverse Transcription real-time polymerase is the technique of molecular biology based on the polymerase chain reaction (PCR), which amplify and simultaneously detect or quantify the targeted RNA molecule of interest. This technique is important in studying the expression of specific genes or the presence of gene mutations.

Microarray

Microarrays consist of probes that are arranged or “arrayed” on a glass chip. These probes could be small fragments of DNA or protein that represent a section of a specific gene’s entire DNA sequence and track the interaction of the captured proteins, respectively. Microarrays are robust tools for diagnostics because they measure large numbers of analytes simultaneously and can answer multiple diagnostic questions with one array.

DNA Sequencing (Sanger Sequencing)

DNA sequencing is the technique of determining the precise order of nucleotides within a DNA molecule. It is used for determining the order of the chemical building blocks, or bases (adenine, cytosine, guanine and thymine) in a given stretch of DNA. Additionally, sequencing is an important tool used for gene alterations detection and can be performed to detect specific mutations.

Next Generation Sequencing

Next-generation sequencing (sometimes called 2nd generation sequencing) has similar properties to Sanger’ DNA sequencing but is much higher throughput, meaning that it can sequence a lot more DNA segments at the same time.